In five patrols, she sank three ships of .
She was sunk on 19 February 1944 by British warships but the entire crew survived and were taken prisoner.
German Type VIIC submarines were preceded by the shorter Type VIIB submarines. U-264 had a displacement of 769t when at the surface and 871t while submerged. She had a total length of 67.1m (220.1feet), a pressure hull length of 50.5m (165.7feet), a beam of 6.2m (20.3feet), a height of 9.6m (31.5feet), and a draught of 4.74m (15.55feet). The submarine was powered by two Germaniawerft F46 four-stroke, six-cylinder supercharged diesel engines producing a total of NaNPS for use while surfaced, two AEG GU 460/8–27 double-acting electric motors producing a total of 750PS for use while submerged. She had two shafts and two 1.23abbr=onNaNabbr=on propellers. The boat was capable of operating at depths of up to .
The submarine had a maximum surface speed of and a maximum submerged speed of . When submerged, the boat could operate for at ; when surfaced, she could travel at . U-264 was fitted with five 53.30NaN0 torpedo tubes (four fitted at the bow and one at the stern), fourteen torpedoes, one 8.82NaN2 SK C/35 naval gun, 220 rounds, and two twin 2sp=usNaNsp=us C/30 anti-aircraft guns. The boat had a complement of between forty-four and sixty.
After training with the 8th U-boat Flotilla, the boat became operational on 1 November 1942 when she was transferred to the 6th flotilla.
U-264s first patrol began when she departed Kiel on 3 November 1942. She entered the Atlantic Ocean after negotiating the gap between the Faroe and the Shetland Islands. On 17 November, she sank the Mount Taurus. She was attacked by a Norwegian corvette, HNoMS Potentilla, on the 20th. No damage was sustained. She entered St. Nazaire in occupied France, on 4 December.
The boat's second sortie was relatively uneventful.
On 26 February 1943 just off Cape Finisterre she fired a salvo of four torpedoes at but all four missed; Sussex had just attacked and sunk the German Tanker Hohenfriedburg.[1] On 17 April 1943, she was in the process of attacking Convoy HX 233 when she was attacked by the escorts. The boat was badly damaged, but was repaired by the crew and the patrol continued. She then sank the Harperley and the West Maximus south of Cape Farewell (Greenland) on 5 May. She docked at Lorient, on the French Atlantic coast, on 1 June.
There then followed a pair of short 'hops' between Lorient and St. Nazaire in August and September 1943.
While on her fourth patrol, U-264 and two other U-boats were re-fuelling from the supply submarine on 4 October 1943 when they were surprised by aircraft from the American carrier . The more nimble Type VIIs escaped, but the 'milch cow' was sunk by the Avengers. U-264 did not remain unscathed for long; later that day she was attacked, the damage inflicted forced a return to base.
For her final sortie, she was again in the North Atlantic. She was damaged by depth charges dropped by the British sloops and and forced to the surface on 19 February 1944 in position 48.5167°N -27°W. Starling opened fire on the submarine, scoring several hits, as the crew abandoned the boat and it then sank.
The entire crew of 52 officers and men were taken prisoner.
U-264 took part in eleven wolfpacks, namely:
| Date | Ship Name | Nationality | Tonnage (GRT) | Fate[2] | |
|---|---|---|---|---|---|
| 17 November 1942 | Mount Taurus |  Greece | 6,696 | Sunk | |
| 5 May 1943 | Harperley |  United Kingdom | 4,586 | Sunk | |
| 5 May 1943 | West Maximus |  United States | 5,561 | Sunk |
The captain of U-264, Captain Hartwig Looks, appears in the 1977 BBC televisions series The Secret War episode 7; "The Battle of the Atlantic".