Gepefrine, also known as 3-hydroxyamphetamine or α-methyl-meta-tyramine and sold under the brand names Pressionorm and Wintonin, is a sympathomimetic medication used as an antihypotensive agent which has been marketed in Germany.[1] [2] [3]
Gepefrine is described as a sympathomimetic and antihypotensive agent.
Gepefrine, also known as 3-hydroxy-α-methylphenethylamine or as 3-hydroxyamphetamine, is a substituted phenethylamine and amphetamine derivative. It is used pharmaceutically as the (S)-enantiomer and as the tartrate salt. Related compounds include meta-tyramine (3-hydroxyphenethylamine), 4-hydroxyamphetamine (norpholedrine), 3,4-dihydroxyamphetamine (α-methyldopamine), and metaraminol ((1R,2S)-3,β-dihydroxyamphetamine), among others.
Gepefrine was synthesized by 1968 and was introduced for medical use in Germany by 1981.[4]
Gepefrine is the generic name of the drug and its .[5] Brand names of gepefrine include Pressionorm and Wintonin.[6]
Gepefrine is a known metabolite of amphetamine in rats.