| Galicano Apacible | |
| Office: | Secretary of Agriculture and Natural Resources |
| Term Start: | 1917 |
| Term End: | 1921 |
| Predecessor: | Post created |
| Successor: | Rafael Corpus |
| Office2: | Member of the Philippine Assembly from Batangas's 1st district |
| Term Start2: | 1909 |
| Term End2: | 1916 |
| Predecessor2: | Felipe Agoncillo |
| Order3: | 5th |
| Office3: | Governor of Batangas |
| Term Start3: | 1907 |
| Term End3: | 1909 |
| Predecessor3: | José Lozada |
| Successor3: | Pablo Borbon |
| Birthname: | Galicano Apacible Antonio y del Castillo |
| Birth Date: | 25 June 1864 |
| Birth Place: | Balayan, Batangas, Captaincy General of the Philippines |
| Death Place: | Manila, Philippines |
| Nationality: | Filipino |
| Party: | Nacionalista |
| Spouse: | Concepcion Castillo |
| Occupation: | Politician |
Galicano Apacible Antonio y del Castillo (June 25, 1864 – March 22, 1949) was a Filipino physician and politician from Batangas. A cousin to José Rizal, he co-founded La Solidaridad and the Nacionalista Party.
He held the office of governor of Batangas from 1907 to 1909 and was the representative of the First District of Batangas to the Philippine Assembly from 1909 to 1916. He was then named Secretary of Agriculture and Natural Resources in 1917,[1] serving until 1921. He is known for his piece To the American People, an Appeal, in which he tried to plead with the people of the United States to pressure its government not to invade his newly independent country.[2]