GPR125 explained
Adhesion G-protein coupled receptor A3 (ADGRA3), also known as GPR125, is an adhesion GPCR that in humans is encoded by the Adgra3 gene[1] [2] (previously Gpr125).
Further reading
- Seandel M . Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. . Nature . 449 . 7160 . 346–50 . 2007 . 17882221 . 2935199 . 10.1038/nature06129. 2007Natur.449..346S . etal.
- Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
- Clark HF, Gurney AL, Abaya E . The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. . Genome Res. . 13 . 10 . 2265–70 . 2003 . 12975309 . 10.1101/gr.1293003 . 403697 . etal.
- Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
- Yamamoto Y, Irie K, Asada M . Direct binding of the human homologue of the Drosophila disc large tumor suppressor gene to seven-pass transmembrane proteins, tumor endothelial marker 5 (TEM5), and a novel TEM5-like protein. . Oncogene . 23 . 22 . 3889–97 . 2004 . 15021905 . 10.1038/sj.onc.1207495 . etal.
- Bjarnadóttir TK, Fredriksson R, Höglund PJ . The human and mouse repertoire of the adhesion family of G-protein-coupled receptors. . Genomics . 84 . 1 . 23–33 . 2005 . 15203201 . 10.1016/j.ygeno.2003.12.004 . etal.
- Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
- Olsen JV, Blagoev B, Gnad F . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . etal. free .
Notes and References
- Fredriksson R, Gloriam DE, Hoglund PJ, Lagerstrom MC, Schioth HB . There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini . Biochem Biophys Res Commun . 301 . 3 . 725–34 . Feb 2003 . 12565841 . 10.1016/S0006-291X(03)00026-3 .
- Web site: Entrez Gene: GPR125 G protein-coupled receptor 125.
