GLRA2 explained

Glycine receptor subunit alpha-2 is a protein that in humans is encoded by the GLRA2 gene.^[1]

See also

• Glycine receptor

Further reading

• Grenningloh G, Schmieden V, Schofield PR . Alpha subunit variants of the human glycine receptor: primary structures, functional expression and chromosomal localization of the corresponding genes . EMBO J. . 9 . 3 . 771–6 . 1990 . 10.1002/j.1460-2075.1990.tb08172.x . 2155780 . 551735 . etal.
• Monani U, Burghes AH . Structure of the human alpha 2 subunit gene of the glycine receptor--use of vectorette and Alu-exon PCR . Genome Res. . 6 . 12 . 1200–6 . 1997 . 8973915 . 10.1101/gr.6.12.1200 . free .
• Huda Zoghbi. Cummings CJ, Dahle EJ, Zoghbi HY . Analysis of the genomic structure of the human glycine receptor alpha2 subunit gene and exclusion of this gene as a candidate for Rett syndrome . Am. J. Med. Genet. . 78 . 2 . 176–8 . 1998 . 9674912 . 10.1002/(SICI)1096-8628(19980630)78:2<176::AID-AJMG16>3.0.CO;2-K .
• Feng J, Craddock N, Jones IR . Systematic screening for mutations in the glycine receptor alpha2 subunit gene (GLRA2) in patients with schizophrenia and other psychiatric diseases . Psychiatr. Genet. . 11 . 1 . 45–8 . 2001 . 11409700 . 10.1097/00041444-200103000-00009 . 5889298 . etal.
• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Davies DL, Crawford DK, Trudell JR . Multiple sites of ethanol action in alpha1 and alpha2 glycine receptors suggested by sensitivity to pressure antagonism . J. Neurochem. . 89 . 5 . 1175–85 . 2004 . 15147510 . 10.1111/j.1471-4159.2004.02390.x . etal. free .
• Miller PS, Harvey RJ, Smart TG . Differential agonist sensitivity of glycine receptor alpha2 subunit splice variants . Br. J. Pharmacol. . 143 . 1 . 19–26 . 2005 . 15302677 . 10.1038/sj.bjp.0705875 . 1575261 .
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Miller PS, Da Silva HM, Smart TG . Molecular basis for zinc potentiation at strychnine-sensitive glycine receptors . J. Biol. Chem. . 280 . 45 . 37877–84 . 2006 . 16144831 . 10.1074/jbc.M508303200 . free .

Notes and References

1. Web site: Entrez Gene: GLRA2 glycine receptor, alpha 2.