| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Francesco Colonna | |
| Church: | Catholic Church |
| Term: | 1642–1653 |
| Predecessor: | Dionisio Tomacelli |
| Successor: | Annibale Sillano |
| Birth Date: | 1597 |
| Birth Place: | Milazzo, Italy |
| Death Date: | 29 Jun 1653 (age 56) |
| Nationality: | Italian |
Francesco Colonna (1597 – 29 Jun 1653) was a Roman Catholic prelate who served as Bishop of Castro di Puglia (1642–1653).[1]
Francesco Colonna was born in Milazzo, Italy in 1597. On 16 Jun 1642, he was appointed during the papacy of Pope Urban VIII as Bishop of Castro di Puglia. On 29 Jun 1642, he was consecrated bishop by Giulio Cesare Sacchetti, Cardinal-Priest of Santa Susanna. He served as Bishop of Castro di Puglia until his death on 29 Jun 1653.