Flavanone 4-reductase explained

In enzymology, a flavanone 4-reductase is an enzyme that catalyzes the chemical reaction

(2S)-flavan-4-ol + NADP⁺

(2S)-flavanone + NADPH + H⁺

Thus, the two substrates of this enzyme are (2S)-flavan-4-ol and NADP⁺, whereas its 3 products are (2S)-flavanone, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is (2S)-flavan-4-ol:NADP⁺ 4-oxidoreductase. This enzyme participates in flavonoid biosynthesis.

References

• Stich K, Forkmann G . 1988 . Biosynthesis of 3-deoxyanthocyanins with flower extracts from Sinningia cardinalis . . 27 . 785–789 . 10.1016/0031-9422(88)84093-7 . 3 .