FRMD6 explained

FERM domain-containing protein 6 is a protein that in humans is encoded by the FRMD6 gene.^[1]

Further reading

• Kronenberg NM, Tilston-Lunel A, Thompson FE, Chen D, Yu W, Dholakia K, Gather MC, Gunn-Moore FJ . 2020 . Willin/FRMD6 Influences Mechanical Phenotype and Neuronal Differentiation in Mammalian Cells by Regulating ERK1/2 Activity . Frontiers in Cellular Neuroscience . 14 . 552213 . 10.3389/fncel.2020.552213. 33088261 . 7498650 . free .
• Moleirinho S, Patrick C, Tilston-Lünel AM, Higginson JR, Angus L, Antkowiak M, Barnett SC, Prystowsky MB, Reynolds PA, Gunn-Moore FJ . 2013 . Willin, an Upstream Component of the Hippo Signaling Pathway, Orchestrates Mammalian Peripheral Nerve Fibroblasts . PLOS ONE . 8 . 4. e60028 . 23593160 . 10.1371/journal.pone.0060028 . 3620498. 2013PLoSO...860028M . free .
• Angus L, Moleirinho S, Herron L, Sinha A, Zhang X, Niestrata M, Dholakia K, Prystowsky MB, Harvey KF, Reynolds PA, Gunn-Moore FJ . Willin/FRMD6 expression activates the Hippo signaling pathway kinases in mammals and antagonizes oncogenic YAP . Oncogene . 31 . 2 . 238–50 . January 2012 . 21666719 . 10.1038/onc.2011.224 . free . 10023/2489 . free .
• Madan R, Brandwein-Gensler M, Schlecht NF, Elias K, Gorbovitsky E, Belbin TJ, Mahmood R, Breining D, Qian H, Childs G, Locker J, Smith R, Haigentz M, Gunn-Moore F, Prystowsky MB . Differential tissue and subcellular expressionof ERM proteins in normal and malignant tissues: cytoplasmic ezrin expression has prognostic significance for head and neck squamous cell carcinoma . Head & Neck . 28 . 11 . 1018–27 . November 2006 . 16783828 . 10.1002/hed.20435 . 32305188 .
• Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C, Jafar-Nejad H, Halder G . The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis . Nature Cell Biology . 8 . 1 . 27–36 . January 2006 . 16341207 . 10.1038/ncb1339 . 15468669 .
• Gunn-Moore FJ, Welsh GI, Herron LR, Brannigan F, Venkateswarlu K, Gillespie S, Brandwein-Gensler M, Madan R, Tavaré JM, Brophy PJ, Prystowsky MB, Guild S . A novel 4.1 ezrin radixin moesin (FERM)-containing protein, 'Willin' . FEBS Letters . 579 . 22 . 5089–94 . September 2005 . 16137681 . 10.1016/j.febslet.2005.07.097 . free .
• Jin J, Smith FD, Stark C, Wells CD, Fawcett JP, Kulkarni S, Metalnikov P, O'Donnell P, Taylor P, Taylor L, Zougman A, Woodgett JR, Langeberg LK, Scott JD, Pawson T . Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization . Current Biology . 14 . 16 . 1436–50 . August 2004 . 15324660 . 10.1016/j.cub.2004.07.051 . 2371325 . free . 2004CBio...14.1436J .

Notes and References

1. Web site: Entrez Gene: FRMD6 FERM domain containing 6.