| Official Name: | Eugene, Missouri |
| Settlement Type: | Unincorporated community |
| Pushpin Map: | Missouri |
| Pushpin Label: | Eugene |
| Pushpin Map Caption: | Location within the state of Missouri |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Missouri |
| Subdivision Type2: | County |
| Subdivision Name2: | Cole |
| Unit Pref: | Imperial |
| Area Footnotes: | [1] |
| Area Total Km2: | 0.87 |
| Area Land Km2: | 0.87 |
| Area Water Km2: | 0.00 |
| Area Total Sq Mi: | 0.34 |
| Area Land Sq Mi: | 0.33 |
| Area Water Sq Mi: | 0.00 |
| Population As Of: | 2020 |
| Population Total: | 140 |
| Population Density Km2: | 161.60 |
| Population Density Sq Mi: | 419.16 |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 827 |
| Coordinates: | 38.3547°N -92.4031°W |
| Postal Code Type: | Zip Code |
| Postal Code: | 65032 |
| Area Code: | 573 |
| Blank Name: | FIPS code |
| Blank Info: | 29-22798 |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 2790921 |
Eugene is an unincorporated community in extreme southwestern Cole County, Missouri, United States. As of the 2020 census, the population is 140.[2] It is located east of Eldon on Route 17, approximately 3miles south of U.S. Route 54.
Eugene was founded in 1904, and named after Eugene Simpson, the original owner of the town site.[3] A post office called Eugene has been in operation since 1904.[4]
Cole County R-V School District is located in Eugene and has a K-12 enrollment of approximately 620 students.[5]