| Eirini Nefrou | |
| Birth Date: | 1994 5, df=yes |
| Birth Place: | Nafplio, Greece |
| Position: | Defender[1] |
| Currentclub: | Panathinaikos |
| Clubnumber: | 23 |
| Youthyears1: | 1999-2010 |
| Youthclubs1: | Akadimia 98 Nafpliou |
| Collegeyears1: | 2015-2017 |
| College1: | Holy Family University |
| Years1: | 2010-2012 |
| Clubs1: | Toxotis Nafpliou |
| Years2: | 2012-2015 |
| Clubs2: | Ikaros Petrotou |
| Years3: | 2017-2020 |
| Clubs3: | PAOK |
| Caps3: | 42 |
| Goals3: | 1 |
| Years4: | 2020 |
| Clubs4: | Diósgyőri |
| Caps4: | 6 |
| Goals4: | 0 |
| Years5: | 2020-2021 |
| Clubs5: | PAOK |
| Caps5: | 3 |
| Goals5: | 0 |
| Years6: | 2021-2022 |
| Clubs6: | Pink Bari |
| Years7: | 2022 |
| Clubs7: | Ternana |
| Caps7: | 7 |
| Goals7: | 1 |
| Years8: | 2023 |
| Clubs8: | Ergotelis |
| Caps8: | 15 |
| Goals8: | 2 |
| Years9: | 2023– |
| Clubs9: | Panathinaikos |
| Caps9: | 24 |
| Goals9: | 2 |
| Nationalyears1: | 2019– |
| Nationalteam1: | Greece |
| Nationalcaps1: | 11 |
| Nationalgoals1: | 0 |
| Pcupdate: | 17 October 2024[2] [3] |
| Ntupdate: | 9 December 2023[4] |
Eirini Nefrou (el|Ειρήνη Νεφρού; born 13 May 1994) is a Greek footballer who plays as a defender for A Division club Panathinaikos and the Greece women's national team.
Nefrou has played for PAOK in Greece at the UEFA Women's Champions League.
Nefrou capped for Greece at senior level during the UEFA Women's Euro 2022 qualifying.