| East Branch Saco River | |
| Pushpin Map: | New Hampshire#USA |
| Pushpin Map Size: | 250 px |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New Hampshire |
| Subdivision Type3: | County |
| Subdivision Name3: | Carroll |
| Subdivision Type4: | Towns |
| Subdivision Name4: | Jackson, Bartlett |
| Length: | 13.2miles |
| Source1 Location: | Jackson |
| Source1 Coordinates: | 44.235°N -71.1253°W |
| Source1 Elevation: | 2130feet |
| Mouth: | Saco River |
| Mouth Location: | Bartlett |
| Mouth Coordinates: | 44.095°N -71.1642°W |
| Mouth Elevation: | 505feet |
| Tributaries Left: | East Fork, Slippery Brook |
The East Branch of the Saco River is a 13.2adj=midNaNadj=mid[1] river in the White Mountains of New Hampshire in the United States. It is a tributary of the Saco River, which flows to the Atlantic Ocean in Maine.
The East Branch rises near the northern boundary of Jackson, New Hampshire, in an area just south of the Wild River, east of Black Mountain Ski Area, and southwest of the Baldface mountains. The river flows south through the White Mountain National Forest in an area that is devoted more to logging than other portions of the forest. Leaving the forest, the river enters the town of Bartlett, reaching the Saco River at Lower Bartlett village, just downstream of the Ellis River confluence with the Saco.