| Domingo Gribeo y Martín | |
| Order: | Mayordomo of |
| Office: | Buenos Aires |
| Term Start: | 1607 |
| Term End: | 1608 |
| Predecessor: | ? |
| Successor: | ? |
| Birth Date: | 1558 |
| Birth Place: | Asunción, Paraguay |
| Death Date: | 1649 |
| Death Place: | Buenos Aires, Argentina |
| Occupation: | Politician |
| Profession: | Army's officer |
| Signature: | Domingo Gribeo, firma.jpg |
| Branch: | Spanish Army |
| Rank: | Captain |
Domingo Gribeo y Martin (1558 - 1649) was a Spanish military man who served during the Viceroyalty of Peru as mayordomo of hospital, and regidor of Buenos Aires.
Gribeo was born in Asuncion, son of Leonardo Gribeo and Isabel Martín, daughter of Manuel Martin, a Spanish conquistador who served as notary public of Asuncion. Domingo Gribeo was married to María Esterlín, daughter of Rodrigo de Esterlín and Juana de Solórzano, belonging to Creole families, among whose many ancestors were the conquerors Arnao Esterlin and Zoilo de Solórzano, born in the Islas Canarias. Domingo had inherited the land from his brother Lazaro Gribeo, neighbor founder of Buenos Aires, companion of Juan de Garay in the second foundation of the city.