| Official Name: | Depce |
| Native Name: | |
| Native Name Lang: | sr |
| Settlement Type: | Village (Selo) |
| Pushpin Map: | Serbia |
| Pushpin Label Position: | right |
| Subdivision Type: | Country |
| Subdivision Name: |  Serbia |
| Subdivision Type1: | District |
| Subdivision Name1: | Pčinja District |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Preševo |
| Unit Pref: | Metric |
| Area Footnotes: | [1] |
| Area Total Km2: | 9.18 |
| Population As Of: | 2002 |
| Population Total: | 441 |
| Population Density Km2: | auto |
| Timezone: | CET |
| Utc Offset: | +1 |
| Timezone Dst: | CEST |
| Utc Offset Dst: | +2 |
| Coordinates: | 42.3597°N 21.5542°W |
| Elevation M: | 799 |
Depce (Serbian: Депце; sq|Depcë) is a village located in the municipality of Preševo, Serbia. According to the 2002 census, the village has a population of 441 people. Of these, 423 (95,91 %) were ethnic Albanians, and 17 (3,85 %) others.[2] Agim Ramadani and his family originally hail from Depce. The Berisha tribe is present here, as well as Agim Ramadani and his family belonging to the tribe.[3]