| Official Name: | Degache |
| Other Name: | دقاش |
| Settlement Type: | Commune and town |
| Pushpin Map: | Tunisia |
| Pushpin Label Position: | bottom |
| Pushpin Map Caption: | Location in Tunisia |
| Subdivision Type: | Country |
| Subdivision Name: |  Tunisia |
| Subdivision Type1: | Governorate |
| Subdivision Name1: | Tozeur Governorate |
| Subdivision Type2: | Delegation(s) |
| Subdivision Name2: | Degache |
| Unit Pref: | Imperial |
| Population As Of: | 2014 |
| Population Total: | 14332 |
| Utc Offset: | +1 |
| Coordinates: | 33.9833°N 21°W |
| Postal Code Type: | Post code |
| Postal Code: | 2260 |
Degache (ar|دقاش), also spelled Degueche, is a Tunisian town and commune situated in the region of Djerid, and part of Tozeur Governorate. It had a population of 14,332 in 2014, and is the biggest town of a delegation bearing its name.
Degache began as an oasis exploited since Roman antiquity. The ancient city of Thagis is situated a few kilometres away.
The town is located on the northern shore of the salt lake Chott el Djerid, 12 km east of Tozeur and 92 km west of Gafsa.
The economy of the town is centred on the exploitation of a rich palm plantation, producing deglet nour dates. A centre for phœnicicoles research has been located there. Degache has also 2 industrial areas. It's also increasingly included in south Tunisian Saharan tourist circuits.
Degache has a railway station on the Gafsa-Tozeur line, part of the Tunisian Railways (SNCFT) network. It is served by the national highways RN3 and RN16, the second one crossing the Chott el Djerid to reach Douz. Nearest airport, 13 km far, is Tozeur–Nefta International Airport.