| Combles-en-Barrois | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Combles-en-Barrois 55.svg |
| Arrondissement: | Bar-le-Duc |
| Canton: | Bar-le-Duc-1 |
| Insee: | 55120 |
| Postal Code: | 55000 |
| Mayor: | Francis Jouron[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | CA Bar-le-Duc - Sud Meuse |
| Coordinates: | 48.7517°N 5.1172°W |
| Elevation M: | 248 |
| Elevation Min M: | 199 |
| Elevation Max M: | 279 |
| Area Km2: | 10.26 |
Combles-en-Barrois (pronounced as /fr/, literally Combles in Barrois) is a commune in the Meuse department in Grand Est in north-eastern France.