| Official Name: | Clio, Louisiana |
| Pushpin Map: | Louisiana#USA |
| Pushpin Label: | Clio |
| Pushpin Label Position: | top |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Louisiana |
| Subdivision Type2: | Parish |
| Subdivision Name2: | Livingston |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 10 |
| Coordinates: | 30.3097°N -90.6097°W |
| Postal Code Type: | ZIP code |
| Postal Code: | 70462 |
| Area Code: | 225 |
| Blank Name: | GNIS feature ID |
| Blank Info: | 534004 |
| Blank1 Name: | FIPS code |
| Blank1 Info: | 22-16025 |
Clio is an unincorporated community in Livingston Parish, Louisiana, United States. The community is located 3miles southwest of Killian and 3miles east of Maurepas on the east bank of Amite River. Clio is only a few feet above sea level and almost completely surrounded by swamps with a small entrance from the northwest side.
The Waterson plantation with a sawmill, sugar mill, and warehouse was located near the bank of the Amite river. In 1962 while being interviewed by the Denham Springs News a local citizen named Winny Smiley the wife of Cyrus Luther Tucker described how Clio looked in 1885: