| Castiglione Messer Raimondo | |
| Official Name: | Comune di Castiglione Messer Raimondo |
| Coordinates: | 42.5333°N 66°W |
| Region: | Abruzzo |
| Province: | Teramo (TE) |
| Frazioni: | Appignano, Borea Santa Maria, Bozzano, Cesi, Colletrimarino, Piane, San Giorgio, Vorghe |
| Mayor: | Danilo Crescia |
| Area Total Km2: | 30 |
| Population Footnotes: | [1] |
| Population Total: | 2398 |
| Population As Of: | 1 January 2009 |
| Population Demonym: | Castiglionesi |
| Elevation M: | 306 |
| Saint: | San Donato Martire |
| Day: | 7 August |
| Postal Code: | 64034 |
| Area Code: | 0861 |
Castiglione Messer Raimondo (locally Castiùne) is a town and comune in the province of Teramo, Abruzzo, central Italy.
It is a medieval borough near the Gran Sasso d'Italia massif. Economy is mostly based on agriculture.