| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Carlo Mannello | |
| Bishop of Termoli | |
| Church: | Catholic Church |
| Diocese: | Diocese of Termoli |
| Term: | 1653–1662 |
| Predecessor: | Antonio Leoncillo |
| Successor: | Fabrizio Maracchi |
| Birth Date: | 1618 |
| Birth Place: | Aversa, Italy |
Carlo Mannello (Latin: Carolus Mannellus) (born 1618) was a Roman Catholic prelate who served as Bishop of Termoli (1653–1662).
Carlo Mannello was born in 1618 in Aversa, Italy.On 3 Feb 1653, he was appointed during the papacy of Pope Innocent X as Bishop of Termoli.He served as Bishop of Termoli until his resignation in 1662.