Camicinal Explained

Camicinal was a motilin agonist investigated for the treatment of gastroparesis.[1] [2] [3] It did not improve enteral feeding intolerance.[4]

Notes and References

  1. Barshop K, Kuo B . 25896703 . The investigational drug camicinal for the treatment of gastroparesis . Expert Opinion on Investigational Drugs . 24 . 1 . 133–140 . January 2015 . 25341626 . 10.1517/13543784.2015.975792 .
  2. Hobson R, Farmer AD, Dewit OE, O'Donnell M, Hacquoil K, Robertson D, Barton ME, Dukes GE . 6 . The effects of camicinal, a novel motilin agonist, on gastro-esophageal function in healthy humans-a randomized placebo controlled trial . Neurogastroenterology and Motility . 27 . 11 . 1629–37 . November 2015 . 26348542 . 10.1111/nmo.12663 .
  3. Chapman MJ, Deane AM, O'Connor SL, Nguyen NQ, Fraser RJ, Richards DB, Hacquoil KE, Vasist Johnson LS, Barton ME, Dukes GE . 6 . The effect of camicinal (GSK962040), a motilin agonist, on gastric emptying and glucose absorption in feed-intolerant critically ill patients: a randomized, blinded, placebo-controlled, clinical trial . Critical Care . 20 . 1 . 232 . August 2016 . 27476581 . 4967996 . 10.1186/s13054-016-1420-4 . free .
  4. Deane AM, Lamontagne F, Dukes GE, Neil D, Vasist L, Barton ME, Hacquoil K, Ou X, Richards D, Stelfox HT, Mehta S, Day AG, Chapman MJ, Heyland DK . Nutrition Adequacy Therapeutic Enhancement in the Critically Ill: A Randomized Double-Blind, Placebo-Controlled Trial of the Motilin Receptor Agonist Camicinal (GSK962040): The NUTRIATE Study . Journal of Parenteral and Enteral Nutrition. 42 . 5 . 949–459 . 2018 . 29957868 . 10.1002/jpen.1038 .

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