CEP104 explained
Centrosomal protein 104kDa is a protein that in humans is encoded by the CEP104 gene.[1] Like its Chlamydomonas ortholog, FAP256, it has been shown to localize to the distal ends of both centrioles in the absence of a cilium. During cilium formation, it is found at the tip of the elongating cilium.[2]
Further reading
- Kumar KN, Babcock KK, Johnson PS, Chen X, Ahmad M, Michaelis EK . Cloning of the cDNA for a brain glycine-, glutamate- and thienylcyclohexylpiperidine-binding protein . Biochemical and Biophysical Research Communications . 216 . 1 . 390–8 . November 1995 . 7488117 . 10.1006/bbrc.1995.2636 .
- Jakobsen L, Vanselow K, Skogs M, Toyoda Y, Lundberg E, Poser I, Falkenby LG, Bennetzen M, Westendorf J, Nigg EA, Uhlen M, Hyman AA, Andersen JS . Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods . The EMBO Journal . 30 . 8 . 1520–35 . April 2011 . 21399614 . 3102290 . 10.1038/emboj.2011.63 .
Notes and References
- Web site: Entrez Gene: Centrosomal protein 104kDa. 2014-06-04 .
- Satish Tammana TV, Tammana D, Diener DR, Rosenbaum J . Centrosomal protein CEP104 (Chlamydomonas FAP256) moves to the ciliary tip during ciliary assembly . Journal of Cell Science . 126 . Pt 21 . 5018–29 . November 2013 . 23970417 . 10.1242/jcs.133439 . 3820246 .