CCDC50 explained

Coiled-coil domain-containing protein 50 is a protein that in humans is encoded by the CCDC50 gene.^{[1] [2] [3]}

Further reading

• Strausberg RL, Feingold EA, Grouse LH . Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. . Proc. Natl. Acad. Sci. U.S.A. . 99 . 26 . 16899–903 . 2003 . 12477932 . 10.1073/pnas.242603899 . 139241 . 2002PNAS...9916899M . etal. free .
• Modamio-Høybjør S, Moreno-Pelayo MA, Mencía A . A novel locus for autosomal dominant nonsyndromic hearing loss (DFNA44) maps to chromosome 3q28-29. . Hum. Genet. . 112 . 1 . 24–8 . 2003 . 12483295 . 10.1007/s00439-002-0836-x . 8152410 . etal.
• Ota T, Suzuki Y, Nishikawa T . Complete sequencing and characterization of 21,243 full-length human cDNAs. . Nat. Genet. . 36 . 1 . 40–5 . 2004 . 14702039 . 10.1038/ng1285 . etal. free .
• Blagoev B, Ong SE, Kratchmarova I, Mann M . Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. . Nat. Biotechnol. . 22 . 9 . 1139–45 . 2005 . 15314609 . 10.1038/nbt1005 . 11707801 .
• Gerhard DS, Wagner L, Feingold EA . The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). . Genome Res. . 14 . 10B . 2121–7 . 2004 . 15489334 . 10.1101/gr.2596504 . 528928 . etal.
• Zhang Y, Wolf-Yadlin A, Ross PL . Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules. . Mol. Cell. Proteomics . 4 . 9 . 1240–50 . 2005 . 15951569 . 10.1074/mcp.M500089-MCP200 . etal. free .
• Olsen JV, Blagoev B, Gnad F . Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. . Cell . 127 . 3 . 635–48 . 2006 . 17081983 . 10.1016/j.cell.2006.09.026 . 7827573 . etal. free .
• Modamio-Hoybjor S, Mencia A, Goodyear R . A mutation in CCDC50, a gene encoding an effector of epidermal growth factor-mediated cell signaling, causes progressive hearing loss. . Am. J. Hum. Genet. . 80 . 6 . 1076–89 . 2007 . 17503326 . 10.1086/518311 . 1867096 . etal.

Notes and References

1. Vazza G, Picelli S, Bozzato A, Mostacciuolo ML . Identification and characterization of C3orf6, a new conserved human gene mapping to chromosome 3q28 . Gene . 314 . 113–20 . Oct 2003 . 14527723 . 10.1016/S0378-1119(03)00710-8 .
2. Tashiro K, Konishi H, Sano E, Nabeshi H, Yamauchi E, Taniguchi H . Suppression of the ligand-mediated down-regulation of epidermal growth factor receptor by Ymer, a novel tyrosine-phosphorylated and ubiquitinated protein . J Biol Chem . 281 . 34 . 24612–22 . Aug 2006 . 16803894 . 10.1074/jbc.M604184200 . free .
3. Web site: Entrez Gene: CCDC50 coiled-coil domain containing 50.