| Burke Building | |
| Location: | 209-211 4th Ave., Pittsburgh, Pennsylvania |
| Coordinates: | 40.44°N -80.0025°W |
| Built: | 1836 |
| Architect: | Chislett, John |
| Architecture: | Greek Revival |
| Added: | September 18, 1978 |
| Refnum: | 78002335 |
| Designated Other1: | PHLF |
| Designated Other1 Date: | 1970[1] |
The Burke Building in downtown Pittsburgh, Pennsylvania is a building from 1836. It was Pittsburgh's first major office building and a major anchor of the city's financial district centered on Fourth Avenue. Since the 1845 Great Fire burned over a thousand buildings, it is the city's only remaining large Greek Revival building. It was listed on the National Register of Historic Places in 1978.