| Brush Creek | |
| Name Other: | Tributary to Niobrara River |
| Map Size: | 300 |
| Pushpin Map: | USA Nebraska#USA |
| Pushpin Map Size: | 300 |
| Pushpin Map Caption: | Location of Brush Creek mouth |
| Pushpin Map Alt: | Map of Brush Creek mouth location |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | Nebraska |
| Subdivision Type3: | County |
| Subdivision Name3: | Holt |
| Length: | 19.52miles[1] |
| Discharge1 Location: | Niobrara River |
| Discharge1 Avg: | 8.74cuft/s at mouth with Niobrara River[2] |
| Source1: | North Branch Eagle Creek divide |
| Source1 Location: | about 3 miles northeast of School No. 89 |
| Source1 Coordinates: | 42.6607°N -98.9129°W[3] |
| Source1 Elevation: | 2051feet |
| Mouth: | Niobrara River |
| Mouth Location: | about 2 miles northwest of School No. 12 |
| Mouth Coordinates: | 42.8264°N -98.8168°W |
| Mouth Elevation: | 1562feet |
| Progression: | Niobrara River → Missouri River → Mississippi |
| River System: | Niobrara |
| Tributaries Right: | Spring Creek |
| Bridges: | 887th Road, 479th Avenue, NE 11 |
Brush Creek is a 19.52miles long second-order tributary to the Niobrara River in Holt County, Nebraska.
Brush Creek rises on the North Branch Eagle Creek divide about northeast of School No. 89 in Holt County and then flows generally north-northeast to join the Niobrara River about northwest of School No. 12.[3]
Brush Creek drains of area, receives about of precipitation, and is about 2.80% forested.[2]