| Brillon-en-Barrois | |
| Commune Status: | Commune |
| Image Coat Of Arms: | Blason ville fr Brillon-en-Barrois 55.svg |
| Arrondissement: | Bar-le-Duc |
| Canton: | Ancerville |
| Insee: | 55079 |
| Postal Code: | 55000 |
| Mayor: | Florent Renaudin[1] |
| Term: | 2020 - 2026 |
| Intercommunality: | Portes de Meuse |
| Coordinates: | 48.7122°N 5.0956°W |
| Elevation M: | 245 |
| Elevation Min M: | 185 |
| Elevation Max M: | 278 |
| Area Km2: | 11.35 |
Brillon-en-Barrois (pronounced as /fr/, literally Brillon-en-Barrois) is a commune in the Meuse department in Grand Est in northeastern France.