| Boca de Huérgano | |
| Native Name: | Boca de Güérganu |
| Native Name Lang: | ast |
| Pushpin Map: | Spain |
| Coordinates: | 42.9736°N -4.9275°W |
| Subdivision Name3: | Boca de Huérgano |
| Leader Title: | Mayor |
| Leader Name: | Tomás de la Sierra González |
| Leader Party: | PP |
| Area Total Km2: | 291.84 |
| Elevation M: | 1111 |
| Population Density Km2: | auto |
| Utc Offset: | +1 |
| Utc Offset Dst: | +2 |
| Postal Code Type: | Postal Code |
| Postal Code: | 24911 |
| Area Code Type: | Telephone prefix |
| Area Code: | 987 |
Boca de Huérgano (pronounced as /es/; ast-ES|Boca de Güérganu) is a village and municipality located in the Montaña Leonesa of province of León, Castile and León, Spain. According to the 2010 census (INE), the municipality has a population of 531 inhabitants.