The men's 4 × 400 metres relay at the 2007 All-Africa Games was held on July 21–22.
| width=200 valign=top | Gakologelwang Masheto Obakeng Ngwigwa Isaac Makwala California Molefe | width=200 valign=top | Bola Lawal Saul Weigopwa Victor Isaiah James Godday | width=200 valign=top | Nelton Ndebele Talkmore Nyongani Gabriel Chikomo Lewis Banda |
Qualification: First 3 teams of each heat (Q) plus the next 2 fastest (q) qualified for the final.
| Rank | Heat | Nation | Athletes | Time | Notes | |
|---|---|---|---|---|---|---|
| 1 | 2 | 3:06.17 | Q | |||
| 2 | 2 | 3:06.65 | Q | |||
| 3 | 2 | 3:06.67 | Q | |||
| 4 | 2 | 3:07.63 | q | |||
| 5 | 1 | 3:08.01 | Q | |||
| 6 | 2 | 3:08.11 | q | |||
| 7 | 1 | 3:08.18 | Q | |||
| 8 | 1 | 3:08.26 | Q | |||
| 9 | 2 | 3:08.26 | ||||
| 10 | 2 | 3:12.03 | ||||
| 11 | 1 | 3:13.21 | ||||
| 12 | 1 | 3:24.19 | ||||
| 1 |
| Rank | Nation | Athletes | Time | Notes | |
|---|---|---|---|---|---|
| 3:03.16 | |||||
| 3:03.99 | |||||
| 3:04.84 | |||||
| 4 | 3:05.32 | ||||
| 5 | 3:06.38 | ||||
| 6 | 3:08.35 | ||||
| 7 | 3:09.37 | ||||