Amycolatopsis rifamycinica explained

Amycolatopsis rifamycinica is a species of Gram-positive bacteria in the genus Amycolatopsis. It produces the rifamycin antibiotics (e.g., rifamycin SV), which are used to treat mycobacterial diseases such as tuberculosis and leprosy.[1] The type strain of Amycolatopsis rifamycinica (DSM 46095) has been reclassified several times. When it was first isolated from a French soil sample in 1957, it was identified as Streptomyces mediterranei.[2] In 1969, the species was renamed Nocardia mediterranei because its cell wall was thought to resemble that of Nocardia species.[3] The species was renamed Amycolatopsis mediterranei in 1986 after finding that it is not susceptible to Nocardia phage and has a cell wall that lacks mycolic acid.[4] Finally, in 2004, it was determined that strain DSM 46095 represented a new species, independent of Amycolatopsis mediterranei, based on 16S ribosomal RNA sequencing. The new species was named Amycolatopsis rifamycinica.

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Notes and References

  1. Saxena A, Kumari R, Mukherjee U, Singh P, Lal R. Draft genome sequence of the rifamycin producer Amycolatopsis rifamycinica DSM 46095. Genome Announcements. 2 . 4. e00662-14. 2014 . 24994803. 10.1128/genomeA.00662-14 . 4082003.
  2. Margalith P, Beretta G. Rifomycin. XI. Taxonomic study on Streptomyces mediterranei nov. sp. . Mycopathol. Mycol. Appl. . 8 . 4. 321–330. 1960 . 10.1007/BF02089930.
  3. Thiemann JE, Zucco G, Pelizza G. A proposal for the transfer of Streptomyces mediterranei Margalith and Beretta 1960 to the genus Nocardia as Nocardia mediterranea (Margalith and Beretta) comb. nov. . Arch. Mikrobiol.. 67 . 2. 147–155. 1969 . 5386179 . 10.1007/bf00409680.
  4. Lechevalier MP, Prauser H, Labeda DP, Ruan JS. Two new genera of nocardioform actinomycetes: Amycolata gen. nov. and Amycolatopsis gen. nov.. Int. J. Syst. Evol. Microbiol.. 36. 1. 29–37. 1986. 10.1099/00207713-36-1-29. free. 2018-12-29. 2021-06-07. https://web.archive.org/web/20210607220020/https://naldc-legacy.nal.usda.gov/naldc/download.xhtml?id=24570&content=PDF. dead.

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