Ampyrone Explained

Ampyrone is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. While the parent drug, aminopyrine, has been discouraged due to the risk of agranulocytosis,[1] [2] ampyrone itself has significantly lower toxicity.[3] It is used as a reagent for biochemical reactions producing peroxides or phenols.[4] Ampyrone stimulates liver microsomes and is also used to measure extracellular water.[4]

Notes and References

  1. Bailey . D. N. . 1983 . The unusual occurrence of 4-aminoantipyrine (4-aminophenazone) in human biological fluids . Journal of Analytical Toxicology . 7 . 2 . 76–78 . 10.1093/jat/7.2.76 . 0146-4760 . 6855207.
  2. Web site: PubChem . Aminopyrine . 2024-08-26 . pubchem.ncbi.nlm.nih.gov . en.
  3. Web site: PubChem . 4-Aminoantipyrine . 2024-08-26 . pubchem.ncbi.nlm.nih.gov . en.
  4. Web site: 25 March 2005. 4-Aminoantipyrine. 2022-05-09. pubchem.ncbi.nlm.nih.gov. en.

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