| Ambrose Senyshyn | |
| Native Name Lang: | uk |
| Native Name: | Амвросій Сенишин |
| Birth Date: | 23 February 1903 |
| Birth Place: | United States |
| Death Place: | United States |
| Occupation: | Ukrainian Catholic prelate |
Ambrose Senyshyn, O.S.B.M (February 23, 1903 – September 11, 1976) was a Ukrainian Catholic prelate who served, beginning in 1958, as Eparch of Stamford. On August 14, 1961, he was appointed Archeparch of Philadelphia.