| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Alfonso de Talavera | |
| Bishop of Comayagua | |
| Church: | Catholic Church |
| Diocese: | Diocese of Comayagua |
| Term: | 1531–1540 |
| Predecessor: | None |
| Successor: | Cristóbal de Pedraza |
Alfonso de Talavera, O.S.H. or Alfonso de Guzman was a Roman Catholic prelate who served as the first Bishop of Comayagua (1531–1540).[1]
Alfonso de Talavera was ordained a priest in the Order of Saint Jerome.[2] In September 1531, he was appointed during the papacy of Pope Clement VII as Bishop of Comayagua.He served as Bishop of Comayagua until his resignation in 1540.