AfaR small RNA explained

In molecular biology, AfaR small RNA is an Hfq-dependent small RNA produced by the bacterium Escherichia coli. It is an Hfq-dependent RNA which downregulates AfaD-VIII invasin translation by binding to and initiating cleavage of its mRNA.^[1]

The transcription of AfaR is dependent on the stress response sigma factor sigma E.

See also

• Bacterial small RNA

Notes and References

1. Pichon. C. du Merle, L. Lequeutre, I. Le Bouguénec, C. The AfaR small RNA controls expression of the AfaD-VIII invasin in pathogenic Escherichia coli strains.. Nucleic Acids Research. Apr 5, 2013. 23563153. 10.1093/nar/gkt208. 41. 10. 5469–5482. 3664800.