AHSA2 explained

AHSA2 also known as AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) is a human gene which encodes a protein which acts as co-chaperone of Hsp90 (heat shock protein 90).^[1] AHSA2 and the related AHSA1 belongs to the AHA (Activator of Hsp90 ATPase) family of stress-regulated proteins that bind directly to Hsp90 and are required for Hsp90-dependent activation of client proteins.^[1]

Notes and References

1. Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, Prodromou C . Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1 . Mol. Cell . 10 . 6 . 1307–18 . December 2002 . 12504007 . 10.1016/S1097-2765(02)00785-2 .