7-ACA explained

7-ACA (7-aminocephalosporanic acid) is the core chemical structure (a synthon) for the synthesis of cephalosporin antibiotics and intermediates. It can be obtained by chemoenzymatic hydrolysis of cephalosporin C.^{[1] [2]}

The production of 7-ACA (7-aminocephalosporanic acid) is predominantly segmented into two methods which is Enzymatic Hydrolysis and Chemical Cracking. These processes are essential for the synthesis of various cephalosporin antibiotics.^[3]

See also

• 6-APA

Notes and References

1. World Journal of Microbiology & Biotechnology . 26 . 1 . 145–152 . 2010 . 10.1007/s11274-009-0153-9 . Single-pot conversion of cephalosporin C to 7-aminocephalosporanic acid in the absence of hydrogen peroxide . Tan . Qiang . Zhang . Yewang . Song . Qingxun . Wei . Dongzhi. 84749385 .
2. Enzyme and Microbial Technology . 39 . 5 . 1166–1172 . 2006 . 10.1016/j.enzmictec.2006.02.028 . Single-pot conversion of cephalosporin C to 7-aminocephalosporanic acid using cell-bound and support-bound enzymes . Tan . Qiang . Song . Qingxun . Wei . Dongzhi.
3. Web site: 7-Aminocephalosporanic Acid (7-ACA) Market . Markets Glob Market Research . 30 August 2024.