4-Methylcyclohexene Explained

4-Methylcyclohexene is an organic compound consisting of cyclohexene with a methyl group substituent attached to carbon most distant from the alkene group. Two other structural isomers are known: 1-methylcyclohexene and 3-methylcyclohexene. All are colorless volatile liquids classified as a cyclic olefins. They are specialized reagents.

Methylcyclohexenes are formed by the partial hydrogenation of toluene to methylcyclohexane over ruthenium catalyst.[1]

In the presence of a Cinchona alkaloid, bromination of an alkene can leads to optically active dibromides.[2] For 4-methylcyclohexene, the (S)-configuration leads to two different products: the bromines can add at the axial positions, giving the orientation (1S,3R,4R), or at the equatorial positions, giving the orientation (1S,3S,4S). Similarly, the (R)-configuration produces two different products: axial addition yields the configuration (1R,3S,4S) and equatorial addition yields (1R,3R,4R).

Notes and References

  1. Belohlav, H. . Kluson, P. . Cerveny, L. . 1997 . Partial Hydrogenation of Toluene Over A Ruthenium Catalyst, A Model Treatment of A Deactivation Process . Res. Chem. Intermed. . 32 . 2 . 161–168 . 10.1163/156856797X00312 . 95532469.
  2. 1969 . Asymmetric Bromination of 4-Methylcyclohexene in the Presence of Dihydrocinchonine . Tetrahedron . Bellucci, G.. Giordano, C.. Marsili, A.. Berti, G. . 25 . 18 . 4515–4522 . 10.1016/S0040-4020(01)82993-8.