3,3-Dimethylbutyraldehyde Explained

3,3-Dimethylbutyraldehyde is a branched saturated aliphatic aldehyde with an unpleasant odor that is used in the synthesis of perfumes and neotame.^[1]

Synthesis

It can be synthesized from 3,3-dimethyl-1-butanol via a copper catalyzed dehydrogenation.^[2]

Other sources

K. Satyavathi, P.B. Raju, K.V. Bupesh, T.N.R. Kiran (2010), "Mini Review. Neotame: High Intensity Low Caloric Sweetener", Asian J. Chem. 7 (22).

Notes and References

1. Prakash . Indra . Bishay . Ihab . Schroeder . Steve . Neotame: Synthesis, Stereochemistry and Sweetness . Synthetic Communications . 1 December 1999 . 29 . 24 . 4461-4467 . 10.1080/00397919908086610 . 12 November 2021 .
2. Tanielyan . Setrak K. . Augustine . Robert L. . Synthesis of 3,3-Dimethylbutanol and 3,3-Dimethylbutanal, Important Intermediates in the Synthesis of Neotame . Topics in Catalysis . Springer Science and Business Media LLC . 55 . 7–10 . 2012-06-22 . 1022-5528 . 10.1007/s11244-012-9841-z . 625–630.