25C-NBOH explained
| Iupac Name: | 2-(methyl)phenol |
| Legal Br: | F2 |
| Legal Br Comment: | [1] |
| Legal De: | NpSG |
| Legal Uk: | Class A |
| Cas Number: | 1391488-16-6 |
| Unii: | P8BP3X5EBR |
| Pubchem: | 125181419 |
| Chemspiderid: | 58191432 |
| C: | 17 |
| H: | 20 |
| Cl: | 1 |
| N: | 1 |
| O: | 3 |
| Smiles: | COc1cc(Cl)c(OC)cc1CCNCc2ccccc2O |
| Stdinchi: | 1S/C17H20ClNO3/c1-21-16-10-14(18)17(22-2)9-12(16)7-8-19-11-13-5-3-4-6-15(13)20/h3-6,9-10,19-20H,7-8,11H2,1-2H3 |
| Stdinchikey: | VHWXICYYQMMZCW-UHFFFAOYSA-N |
25-C-NBOH (2C-C-NBOH, NBOH-2CC) is a derivative of the phenethylamine derived hallucinogen 2C-C which has been sold as a designer drug. It has similar serotonin receptor affinity to the better-known compound 25C-NBOMe.[2] [3]
Analogues and derivatives
Analytical chemistry
25C-NBOH undergoes degradation under routine Gas Chromatography (GC) conditions, as well as other NBOH's substances, into 2C-C.[4] [5] An alternative method proposed for reliable identification of 25I-NBOH using GC/MS may be used for 25C-NBOH analysis.[6] [7]
Legality
United Kingdom
Notes and References
- Web site: Anvisa . Brazilian Health Regulatory Agency . 2023-07-24 . RDC Nº 804 - Listas de Substâncias Entorpecentes, Psicotrópicas, Precursoras e Outras sob Controle Especial . Collegiate Board Resolution No. 804 - Lists of Narcotic, Psychotropic, Precursor, and Other Substances under Special Control. live . https://web.archive.org/web/20230827163149/https://www.in.gov.br/en/web/dou/-/resolucao-rdc-n-804-de-24-de-julho-de-2023-498447451 . 2023-08-27 . 2023-08-27 . . pt-BR . 2023-07-25.
- Hansen M, Phonekeo K, Paine JS, Leth-Petersen S, Begtrup M, Bräuner-Osborne H, Kristensen JL . Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists . ACS Chemical Neuroscience . 5 . 3 . 243–9 . March 2014 . 24397362 . 3963123 . 10.1021/cn400216u .
- Hansen M . Design and Synthesis of Selective Serotonin Receptor Agonists for Positron Emission Tomography Imaging of the Brain. . Ph.D. . University of Copenhagen . 2010-12-16 . 10.13140/RG.2.2.33671.14245.
- Arantes LC, Júnior EF, de Souza LF, Cardoso AC, Alcântara TL, Lião LM, Machado Y, Lordeiro RA, Neto JC, Andrade AF . 6 . 2A receptor agonist identified in blotter paper seizures in Brazil . Forensic Toxicology . 35 . 2 . 408–414 . 2017 . 28706567 . 5486617 . 10.1007/s11419-017-0357-x .
- Machado Y, Lordeiro RA, Neto JC, Alves RB, Piccin E . Identification of new NBOH drugs in seized blotter papers: 25B-NBOH, 25C-NBOH, and 25E-NBOH . Forensic Toxicology . 38 . 2 . 203–215 . 2019 . 10.1007/s11419-019-00509-7 . 209672508 . free .
- Neto JC, Andrade AF, Lordeiro RA, Machado Y, Elie M, Júnior EF, Arantes LC . Preventing misidentification of 25I-NBOH as 2C-I on routine GC–MS analyses. Forensic Toxicology. 35. 2. 415–420. 2017 . 10.1007/s11419-017-0362-0 . 32432586.
- Machado Y, Lordeiro RA, Neto JC, Alves RB, Piccin E . Identification of new NBOH drugs in seized blotter papers: 25B-NBOH, 25C-NBOH, and 25E-NBOH . Forensic Toxicology . 38 . 2 . 203–215 . 2019 . 10.1007/s11419-019-00509-7 . 209672508 . free .
