| Date: | 11–16 September |
| Edition: | 6th |
| Surface: | Hard |
| Location: | Guangzhou, China |
| Champs: |  Térence Atmane |
| Champd: | Antoine Bellier / Luca Castelnuovo |
| Before Name: | "GDD CUP" International Challenger Guangzhou |
| Before Year: | 2016 |
The 2023 Guangzhou International Challenger was a professional tennis tournament played on hard courts. It was the 6th edition of the tournament which was part of the 2023 ATP Challenger Tour. It took place in Guangzhou, China between 11 and 16 September 2023.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 Australia | Christopher O'Connell | 69 | 1 | |
| Australia | Marc Polmans | 174 | 2 | |
 China | Shang Juncheng | 178 | 3 | |
| China | Bu Yunchaokete | 214 | 4 | |
| France | Térence Atmane | 218 | 5 | |
 Japan | Rio Noguchi | 251 | 6 | |
| Evgeny Donskoy | 255 | 7 | ||
| Australia | Li Tu | 256 | 8 |
The following players received wildcards into the singles main draw:
The following player received entry into the singles main draw as an alternate:
The following players received entry from the qualifying draw:
Arjun Kadhe Sun Qian Wang AoranSee main article: 2023 Guangzhou International Challenger – Singles.
Térence Atmane def. Marc Polmans 4–6, 7–6(9–7), 6–4.See main article: 2023 Guangzhou International Challenger – Doubles.
Matthew Romios 6–3, 7–6(7–5).