| Tourney Name: | Senior League World Series |
| Year: | 2022 |
| Country: | United States |
| Num Teams: | 12 |
| Champion Other: |  Guayama, Puerto Rico |
| Second Other: | Norfolk, Virginia |
| Prevseason: | 2019 |
| Nextseason: | 2023 |
The 2022 Senior League World Series took place from July 30–August 6 in Easley, South Carolina. Guayama, Puerto Rico defeated Norfolk, Virginia in the championship game. This was the first Senior Little League World Series held since the COVID-19 pandemic.
| United States | International | |
|---|---|---|
| Easley, South Carolina District 1 (Easley) Host |  GuamGuam District 1 Asia–Pacific | |
| Burbank, Illinois Burbank American Central |  Melbourne, VictoriaEastern Athletics Baseball Charter Australia | |
| Vineland, New Jersey East Vineland East |  Mirabel, QuebecDiamond Baseball Canada | |
| Norfolk, Virginia Fleet Park Southeast |  Nettuno, ItalyLazio Europe–Africa | |
| Houston, Texas West University Southwest |  Aguadulce, PanamaAguadulce Cabezera Latin America | |
| Wailuku, Hawaii Central East Maui West | Guayama, Puerto Rico Radamés López Caribbean |
United States Bracket
International Bracket
World Championship