| Date: | 27 June – 3 July |
| Edition: | 2nd |
| Surface: | Clay |
| Location: | Lüdenscheid, Germany |
| Champs: |  Hamad Međedović |
| Champd: | Robin Haase / Sem Verbeek |
The 2022 Platzmann-Sauerland Open was a professional tennis tournament played on clay courts. It was the second edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Lüdenscheid, Germany, between 27 June and 3 July 2022.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Nicolás Jarry | 129 | 1 | ||
| Mats Moraing | 142 | 2 | ||
 France | Manuel Guinard | 154 | 3 | |
 Italy | Marco Cecchinato | 171 | 4 | |
 Argentina | Santiago Rodríguez Taverna | 179 | 5 | |
| Dominic Stricker | 188 | 6 | ||
| Pablo Cuevas | 189 | 7 | ||
 Slovakia | Filip Horanský | 195 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry into the singles main draw as alternates:
The following players received entry from the qualifying draw:
Georgii Kravchenko Hamad Međedović
Mohamed SafwatThe following player received entry as a lucky loser:
See main article: 2022 Platzmann-Sauerland Open – Singles.
Hamad Međedović def. 
Zhang Zhizhen 6–1, 6–2.See main article: 2022 Platzmann-Sauerland Open – Doubles.
