| Date: | 22–28 August |
| Edition: | 1st |
| Surface: | Hard |
| Location: | Nonthaburi, Thailand |
| Champs: | Valentin Vacherot |
| Champd: | Evgeny Donskoy / Alibek Kachmazov |
| After Name: | Nonthaburi Challenger II |
| After Year: | 2022 |
The 2022 Nonthaburi Challenger was a professional tennis tournament played on hard courts. It was the 1st edition of the tournament which was part of the 2022 ATP Challenger Tour. It took place in Nonthaburi, Thailand from 22 to 28 August 2022.
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
 United Kingdom | Alastair Gray | 255 | 1 | |
 Japan | Yasutaka Uchiyama | 260 | 2 | |
 Kazakhstan | Denis Yevseyev | 263 | 3 | |
| United Kingdom | Billy Harris | 294 | 4 | |
 Brazil | Gabriel Décamps | 302 | 5 | |
 Israel | Yshai Oliel | 307 | 6 | |
| Nicola Kuhn | 320 | 7 | ||
 Ukraine | Illya Marchenko | 322 | 8 |
The following players received wildcards into the singles main draw:
The following players received entry from the qualifying draw:
See main article: 2022 Nonthaburi Challenger – Singles.
See main article: 2022 Nonthaburi Challenger – Doubles.
Nam Ji-sung / Song Min-kyu 6–3, 1–6, [10–7].
Gage Brymer
