| Date: | 31 May – 5 June |
| Edition: | 16th |
| Category: | WTA 125 |
| Location: | Makarska, Croatia |
| Venue: | Tennis Center Makarska |
| Surface: | Clay |
| Prize Money: | $115,000 |
| Champs: | Jule Niemeier |
| Champd: | Dalila Jakupović / Tena Lukas |
| Before Name: | Bol Open |
The 2022 Makarska International Championships, also known as Makarska Open hosted by Valamar, was a professional tennis tournament played on outdoor clay courts. It was the sixteenth edition of the tournament and part of the 2022 WTA 125 tournaments. The previous editions of the tournament were held in Bol as the Croatia Bol Ladies Open but in 2022, the event was relocated to Makarska which once hosted a WTA Tier-IV event in 1998. It took place from 31 May to 5 June 2022.[1]
| Country | Player | Rank1 | Seed | |
|---|---|---|---|---|
| Varvara Gracheva | 71 | 1 | ||
 Italy | Lucia Bronzetti | 73 | 2 | |
| Anastasia Potapova | 80 | 3 | ||
 Poland | Magdalena Fręch | 89 | 4 | |
 Slovakia | Anna Karolína Schmiedlová | 92 | 5 | |
 France | Clara Burel | 94 | 6 | |
| Jule Niemeier | 102 | 7 | ||
 Georgia | Ekaterine Gorgodze | 108 | 8 |
The following players received a wildcard into the singles main draw:
The following players entered the singles main draw through qualification:
Eri Hozumi
Anna Bondár → replaced by Anastasia Gasanova
Madison Brengle → replaced by 
Linda Nosková Dalma Gálfi → replaced by 
Wang Xiyu
Beatriz Haddad Maia → replaced by Réka Luca Jani
Marta Kostyuk → replaced by Viktoriya Tomova Kristína Kučová → replaced by 
Olga Danilović Kristina Mladenovic → replaced by Anastasia Tikhonova
Nuria Párrizas Díaz → replaced by Jule Niemeier
Rebecca Peterson → replaced by Ekaterine Gorgodze Elisabetta Cocciaretto
Mayar Sherif → replaced by Aleksandra Krunić Martina Trevisan → replaced by Elina Avanesyan
Maryna Zanevska → replaced by 
Astra Sharma Zheng Qinwen → replaced by 
Julia Grabher| Country | Player | Country | Player | Rank1 | Seed | |
|---|---|---|---|---|---|---|
| Anastasia Potapova | Yana Sizikova | 184 | 1 | |||
| Julia Lohoff | Czech Republic | Renata Voráčová | 192 | 2 |
See main article: 2022 Makarska International Championships – Singles.
Elisabetta Cocciaretto 7–5, 6–1See main article: 2022 Makarska International Championships – Doubles.
Olga Danilović / Aleksandra Krunić 5–7, 6–2, [10–5]