| Competition: | Segunda División |
| Season: | 2021 |
| Winners: | Albion (1st title) |
| Promoted: | Albion Danubio Defensor Sporting |
| Relegated: | Villa Teresa Rocha |
| Matches: | 115 |
| Total Goals: | 256 |
| Prevseason: | 2020 |
| Nextseason: | 2022 |
The 2021 Uruguayan Segunda División was the season of second division professional of football in Uruguay. A total of 12 teams competed; the top two teams and the winner of the Championship play-offs were promoted to the Uruguayan Primera División.[1] [2]
On 19 March 2021, Nicolás Siri became the youngest hat-trick scorer in the history of Uruguayan football and the second in South America behind Pelé, after scoring a hat-trick in Danubio's 5–1 win against Boston River, at the age of 16 years and 11 months.
| Club | City | Stadium | Capacity | |
|---|---|---|---|---|
| Albion | Montevideo | Parque Enrique Falco | 2,000 | |
| Atenas | San Carlos | Atenas | 6,000 | |
| Central Español | Montevideo | Parque Palermo | 6,500 | |
| Cerro | Montevideo | Luis Trócolli | 24,000 | |
| Danubio | Montevideo | Jardines del Hipódromo | 14,401 | |
| Defensor Sporting | Montevideo | Luis Franzini | 18,000 | |
| Juventud | Las Piedras | Parque Artigas | 12,000 | |
| Racing | Montevideo | Osvaldo Roberto | 8,500 | |
| Rampla Juniors | Montevideo | Olímpico | 9,500 | |
| Rocha | Rocha | Doctor Mario Sobrero | 10,000 | |
| Uruguay Montevideo | Montevideo | Parque ANCAP | 4,000 | |
| Villa Teresa | Montevideo | José Nasazzi | 5,002 |
Defensor Sporting won 3–0 on aggregate and were promoted to Primera División.
| width=28 | width=185 | Team | width=50 | width=50 | width=50 | width=50 | width=50 | Relegation | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Danubio | — | 41 | 41 | 22 | |||||||||
| 2 | Defensor Sporting | — | 37 | 37 | 22 | |||||||||
| 3 | Cerro | — | 37 | 37 | 22 | |||||||||
| 4 | Racing | 30 | 38 | 68 | 44 | |||||||||
| 5 | Albion | 22 | 44 | 66 | 44 | |||||||||
| 6 | Juventud | 32 | 29 | 61 | 44 | |||||||||
| 7 | Central Español | 27 | 33 | 60 | 44 | |||||||||
| 8 | Rampla Juniors | 32 | 21 | 53 | 44 | |||||||||
| 9 | Uruguay Montevideo | — | 25 | 25 | 22 | |||||||||
| 10 | Atenas | 24 | 24 | 48 | 44 | |||||||||
| 11 | Villa Teresa (R) | 26 | 18 | 44 | 44 | Relegation Playoff Matches | ||||||||
| 12 | Rocha (R) | 27 | 15 | 42 | 44 | Relegation to Primera División Amateur | ||||||||
Tied 3–3 on aggregate. La Luz won on penalties and were promoted to Segunda División.
| Rank | Player | Club | Goals | ||
|---|---|---|---|---|---|
| align=center | 1 | Diego Coelho | Cerro | align=center | 24 |
| align=center | 2 | Diego Vera | Defensor Sporting | align=center | 23 |
| 3 | Matías Britos | Atenas | 22 | ||
| Pablo González | Albión | ||||
| Alejo Cruz | Racing |