| Champ: |  Elise Mertens |
| Runner: |  Kaia Kanepi |
| Score: | 6–4, 6–1 |
| Edition: | 1st |
| Type: | singles doubles |
| Main Name: | Australian Open Series |
See main article: 2021 Gippsland Trophy.
The Gippsland Trophy was a new addition to the WTA Tour in 2021.
Elise Mertens won the title, defeating Kaia Kanepi in the final, 6–4, 6–1.[1] [2]
Due to a delayed schedule because of a COVID-19 case at a tournament quarantine hotel, all matches from the quarterfinal stage forward played a match tiebreaker in the final set (first to ten points, win by two).
The top ten seeds received a bye into the second round.
See also: 1 and 1. 
Simona Halep (quarterfinals)
See also: 2 and 4. 
Naomi Osaka (semifinals, withdrew)
See also: 3 and 3. 
Elina Svitolina (quarterfinals)
See also: 4 and 2. 
Aryna Sabalenka (second round)
See also: 5 and 4. 
Johanna Konta (third round)
See also: 6 and 1. 
Iga Świątek (third round)
See also: 7 and 3. Elise Mertens (champion)
See also: 8 and 2. 
Karolína Muchová (quarterfinals, withdrew)
See also: 9 and 1. 
Ekaterina Alexandrova (semifinals)
See also: 10 and 2. 
Wang Qiang (second round)
See also: 11 and 4. Zheng Saisai (first round)
See also: 12 and 3. 
Caroline Garcia (third round)
See also: 13 and 3. Jeļena Ostapenko (third round)
See also: 14 and 4. 
Coco Gauff (second round)
See also: 15 and 2. Polona Hercog (second round)
See also: 16 and 1. Laura Siegemund (third round)