| Champ: |  Jannik Sinner |
| Runner: |  Diego Schwartzman |
| Score: | 6–2, 6–2 |
| Draw: | 28 (4 / 3) |
| Seeds: | 8 |
| Type: | singles doubles |
| Main Name: | European Open (tennis) European Open |
| Before Name: | European Open |
| After Name: | European Open |
See main article: article and 2021 European Open.
Ugo Humbert was the defending champion, but chose not to participate this year.[1]
Jannik Sinner won the title, defeating Diego Schwartzman in the final, 6–2, 6–2.
The top four seeds received a bye into the second round.