| Year: | 2021 |
| Team: | Albany Great Danes |
| Sport: | football |
| Conference: | Colonial Athletic Association |
| Short Conf: | CAA |
| Record: | 2–9 |
| Conf Record: | 1–7 |
| Head Coach: | Greg Gattuso |
| Hc Year: | 8th |
| Off Coach: | Joe Davis |
| Oc Year: | 4th |
| Def Coach: | Joe Bernard |
| Dc Year: | 4th |
| Stadium: | Bob Ford Field at Tom & Mary Casey Stadium |
The 2021 Albany Great Danes football team represented the University at Albany, SUNY as a member of the Colonial Athletic Association (CAA) during the 2021 NCAA Division I FCS football season. Led by eighth-year head coach Greg Gattuso, the Great Danes compiled an overall record of 2–9 with a mark of 1–7 in conference play, placing last out of 12 teams in the CAA. The team played home games at Bob Ford Field at Tom & Mary Casey Stadium in Albany, New York.