| Competition: | Tanzanian Premier League |
| Season: | 2021–22 |
| Winners: | Young Africans S.C. |
| Promoted: | Ihefu F.C. Singida Big Stars |
| Relegated: | Mbeya Kwanza Biashara United |
| Continentalcup1: | Champions League |
| Continentalcup1 Qualifiers: | Young Africans S.C. Simba S.C. |
| Continentalcup2: | Confederation Cup |
| Continentalcup2 Qualifiers: | Azam F.C. |
| Matches: | 240 |
| Total Goals: | 471 |
| League Topscorer: | George Mpole (17 goals) |
| Longest Unbeaten: | 30 (Young Africans S.C.) |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
| Updated: | 9 August 2022 |
The 2021–22 Tanzanian Premier League (known as the NBC Premier League for sponsorship reasons)[1] was the 57th season of the Tanzanian Premier League, the top-tier football league in Tanzania (mainland only), since its establishment in 1965. The season started on 27 September 2021. The season ended with Young Africans S.C. clinching their 28th premier league title, winning the entire season undefeated.[2]
All Teams that participate get a prize money depending on their position in the league.[3]
| Position | Prize Money (TZS) | |
|---|---|---|
| 1st | 600m/- | |
| 2nd | 300m/- | |
| 3rd | 225m/- | |
| 4th | 200m/- | |
| Relegated Teams | 10m/- |
| Rank | Player | Team | Goals |
|---|---|---|---|
| 1 |  Fiston Mayele | Yanga | 17 |
| George Mpole | Geita Gold | ||
| 3 | Reliants Lusajo | Namungo | 10 |
| 4 | Matheo Anthony | KMC | 9 |
| Rodgers Kola | Azam | ||
| 6 | Kibu Denis | Simba | 8 |
| 7 | Anuary Jabir | Dodoma Jiji | 7 |
| Jeremiah Juma | Tanzania Prisons | ||
 Meddie Kagere | Simba | ||
 Saidi Ntibazonkiza | Yanga | ||
| Abdul Suleiman | Coastal Union |
| Player | For | Against | Score | Date | |
|---|---|---|---|---|---|
| Jeremiah Juma | Tanzania Prisons | Namungo | 3-1 | 20 November 2021 | |
| Shiza Kichuya | Namungo | Ntibwa Sugar | 2-4 | 26 June 2022 | |
| Idris Mbombo | Azam | Biashara United | 4-1 | 29 June 2022 |