| Mode: | Women's Basketball |
| Year: | 2021–22 |
| Prev Year: | 2020–21 |
| Next Year: | 2022–23 |
| Team: | St. John's Red Storm |
| Conference: | Big East Conference |
| Short Conf: | Big East |
| Record: | 12–19 |
| Conf Record: | 7–12 |
| Hc Year: | 10th |
| Asst Coach1: | Bill Ferrara |
| Asst Coach2: | Shenneika Smith |
| Asst Coach3: | Candice Walker |
The 2021–22 St. John's Red Storm women's basketball team represent St. John's University during the 2021–22 NCAA Division I women's basketball season. The Red Storm, led by tenth-year head coach Joe Tartamella, play their games at Carnesecca Arena and are members of the Big East Conference.