| Club: | Cape Town Tigers |
| Season: | 2021–22 |
| Owner: | Raphael Edwards |
| Manager: | Relton Booysen |
| League Result: | Champions |
| Cup1: | Basketball Africa League |
| Cup1 Result: | Quarterfinals (eliminated by US Monastir) |
| Prevseason: | 2020–21 |
| Nextseason: | 2022–23 |
The 2021–22 Cape Town Tigers season is the 2nd season in the existence of the Cape Town Tigers. The team played in the BAL qualification and successfully advanced to the 2022 BAL season.
Cape Town began its qualification October 21, 2021 and started its debut season in the BAL on April 10, 2022. The Tigers were led by head coach Relton Booysen.
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|-!colspan=12 style=""|Group stage|-!colspan=12 style=""|Final|-|}
See also: 2022 BAL qualification.
|-!colspan=12 style=""|First round|-!colspan=12 style=""|Elite 16|-
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See also: 2022 BAL season.
|-!colspan=12 style=""|Group phase|-!colspan=12 style=""|Playoffs|}