| Mode: | Women's Basketball |
| Year: | 2020–21 |
| Prev Year: | 2019–20 |
| Next Year: | 2021–22 |
| Team: | UMass Lowell River Hawks |
| Conference: | America East Conference |
| Short Conf: | America East |
| Record: | 12–9 |
| Conf Record: | 10–6 |
| Head Coach: | Denise King |
| Hc Year: | 1st |
| Asst Coach1: | Faisal Khan |
| Asst Coach2: | Stefanie Murphy |
| Asst Coach3: | Dianna Thomas |
| Stadium: | Costello Athletic Center Tsongas Center |
The 2020–21 UMass Lowell River Hawks women's basketball team represented the University of Massachusetts Lowell during the 2020–21 NCAA Division I women's basketball season. The River Hawks were led by first year head coach Denise King and played most their home games in the Costello Athletic Center while select games were played in the Tsongas Center at UMass Lowell. They were members of the America East Conference. They finished the season 12–9, 10–6 in America East play to finish in fourth place.
All non-televised home games and conference road games will stream on either ESPN3 or AmericaEast.tv. Most road games will stream on the opponents website.
[1] |-!colspan=9 style=| Non-conference regular season|-!colspan=9 style=| America East regular Season|-!colspan=9 style=| America East Women's Tournament