| Competition: | Serbian First League |
| Season: | 2020–21 |
| Winners: | Radnički 1923 |
| Promoted: | Radnički 1923 Kolubara |
| Relegated: | Borac 1926 Dinamo Dubočica Trayal Radnički Pirot Sloga Kraljevo Zemun Jagodina |
| League Topscorer: | Dragiša Komarčević (14 goals) |
| Biggest Home Win: | Loznica 7–0 Dubočica |
| Biggest Away Win: | Trayal 0–4 Borac 1926 |
| Highest Scoring: | Loznica 4–4 Borac 1926 |
| Matches: | 306 |
| Total Goals: | 704 |
| Longest Wins: | Kabel 7 games |
| Longest Unbeaten: | Radnički 1923 12 games |
| Longest Winless: | Jagodina 16 games |
| Longest Losses: | Sloga 6 games |
| Prevseason: | 2019–20 |
| Nextseason: | 2021–22 |
The 2020–21 Serbian First League was the 16th season of the Serbian First League since its establishment.
The league consisted of 18 teams: ten teams from the 2019–20 Serbian First League and eight new teams promoted from 2019–20 Serbian League. Teams played each other in double round-robin format, with top two teams being promoted to Serbian SuperLiga and bottom eight teams being relegated to Serbian League.
The following teams have changed division since the 2019–20 season.
Promoted from Serbian League
Relegated to Serbian League
Promoted to 2020–21 Serbian SuperLiga
| Team | City | Stadium | Capacity | |
|---|---|---|---|---|
| Borac 1926 | Čačak | Čačak City Stadium | 8,000 | |
| Budućnost Dobanovci | Dobanovci | FK Budućnost Dobanovci Stadium | 1,000 | |
| Dinamo | Vranje | Stadion Yumco | 4,000 | |
| Dubočica | Leskovac | Leskovac City Stadium | 7,000 | |
| Grafičar | Belgrade | Topčiderska zvezda | 1,000 | |
| IMT | Belgrade | Stadion FK IMT | 1,150 | |
| Jagodina | Jagodina | Jagodina City Stadium | 15,000 | |
| Kabel | Novi Sad | FK Kabel Stadium | 2,000 | |
| Kolubara | Lazarevac | FK Kolubara Stadium | 2,500 | |
| Loznica | Loznica | Lagator Stadium | 5,000 | |
| Radnički 1923 | Kragujevac | Čika Dača | 15,100 | |
| Radnički | Pirot | Stadion Dragan Nikolić | 13,816 | |
| Radnički | Sremska Mitrovica | Stadion FK Radnički | 2,000 | |
| Sloga | Kraljevo | Kraljevo City Stadium | 4,000 | |
| Trayal | Kruševac | FK Trayal Stadium | 1,500 | |
| Zemun | Belgrade | Zemun Stadium | 9,588 | |
| Žarkovo | Belgrade | FK Žarkovo Stadium | 610 | |
| Železničar | Pančevo | SC Mladost | 1,200 |
Note: Flags indicate national team as has been defined under FIFA eligibility rules. Players and Managers may hold more than one non-FIFA nationality.
Nike is the official ball supplier for Serbian First League.
Kelme is the official sponsor of the Referee's Committee of the Football Association of Serbia.
| Team | Outgoing manager | Manner of departure | Date of vacancy | Position in table | Incoming manager | Date of appointment | |
|---|---|---|---|---|---|---|---|
| Sloga |  Petar Divić | Sacked | 06 September 2020 | 18th | Boris Bunjak[2] | 06 September 2020 | |
| Radnički Pirot | Dejan Čelar[3] | Resigned | 11 September 2020 | 10th | Nikola Puača[4] | 25 September 2020 | |
| Grafičar | Milija Žižić[5] | Resigned | 14 September 2020 | 6th | Radomir Koković[6] | 23 September 2020 | |
| Dubočica | Aleksandar Kuzmanović[7] | Resigned | 21 September 2020 | 15th | Saša Mrkić[8] | 22 September 2020 | |
| Radnički Pirot | Nikola Puača[9] | Resigned | 11 April 2021 | 16th | Dragan Perišić[10] | 15 April 2021 |
| Team | Player 1 | Player 2 | Player 3 | Player 4 | Naturalized Players | |
|---|---|---|---|---|---|---|
| Borac Čačak |  Joseph Bempah | Abdul Rashid Obuobi |  Stanislav Goldin | |||
| Budućnost Dobanovci |  Emeka Emerun |  Lee Jong-chan |  Michel Vaillant | |||
| Dinamo Vranje |  Miroslav Orlić |  Val Baiano |  → Marko Čubrilo | |||
| Dubočica | Okomayin Segun Onimisi |  Maksym Andrushchenko |  → Dušan Savić | |||
| Grafičar |  Richard Odada | Vanja Panić | Preslav Petrov |  Norman Campbell | → Aleksandar Todorovski | |
| IMT |  Ismaël Béko Fofana | → Dimitrios Tzinovits | ||||
| Jagodina | ||||||
| Kabel | Cyril Nebo |  Petar Pavlićević | ||||
| Kolubara | Arsen Knežević | |||||
| Loznica | → Branislav Ružić → Mihailo Bogićević | |||||
| Žarkovo | Kyril Pakhonov | → Nemanja Šćekić→ Nenad Kiso | ||||
| Radnički 1923 | ||||||
| Radnički Pirot | Marko Gjorgjievski | Guy Edoa | ||||
| Radnički Sremska Mitrovica | Milan Jelovac | Sadick Abubakar |  Revaz Injgia | |||
| Sloga Kraljevo | Moses John | → Marko Vidović→ Marko Mihajlović | ||||
| Trayal | Ousman Joof | Mirko Drašković | ||||
| Zemun | Nikola Pejović | |||||
| Železničar | Zakaria Suraka | → Georgije Jankulov |
For the list of transfers involving First League clubs during 2020–21 season, please see: List of Serbian football transfers summer 2020.
As of matches played on 19 May 2021.[11]
| Pos | Scorer | Teams | Goals |
|---|---|---|---|
| 1 | Dragiša Komarčević | Loznica | 14 |
| 2 | Dušan Savić | Dubočica | 12 |
| Aleksandar Mesarović | Kabel | ||
| 4 | Goran Matić | Loznica | 11 |
| Slobodan Stanojlović | Loznica | ||
| Player | For ! | Against | Result | Date |
|---|---|---|---|---|
| Grafičar | 5–1 | |||
| Dubočica | 3–2 | |||
| Železničar | 5–2 | |||
| Loznica | 6–0 | |||